Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004149 | 0.77 | ALK (0.50) | ALK | |
| SCHEMBL21443150 | 0.70 | ALK (0.35) | ALK | |
| SCHEMBL20004601 | 0.69 | ALDH1A1 (0.34) | ALK | |
| SCHEMBL20004151 | 0.58 | ALK (0.51) | ALK | |
| SCHEMBL897370 | 0.57 | ALK (0.75) | ALK | |
| SCHEMBL897744 | 0.55 | ALK (0.50) | ALK | |
| SCHEMBL16775676 | 0.54 | ALK (0.47) | ALK | |
| SCHEMBL27087539 | 0.53 | ALK (0.48) | ALK | |
| SCHEMBL896950 | 0.53 | CA1 (0.40) | ALK | |
| SCHEMBL25446306 | 0.52 | ALK (0.43) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |
| EP-3345903-A1 | TETRACYCLIC COMPOUNDS | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-07-11 | — | — | EP | disclosed |