Methacrylic Acid

Methacrylic Acid

SCHEMBL2036670

C=C(C)C(=O)O.OCC1CC2C=CC1C2

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 13/20 0.45
ALDH1A1 P00352 6/20 0.41
TDP1 Q9NUW8 3/20 0.41
PKM P14618 3/20 0.39
MAPT P10636 2/20 0.39
MAPK1 P28482 1/20 0.39
LMNA P02545 2/20 0.37
POLB P06746 2/20 0.36
ALOX15 P16050 1/20 0.36
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TSHR P16473 1/20 0.34
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5066177 1.00 KDM4E (0.45) KDM4EALDH1A1TDP1PKMMAPT
Acetic Acid SCHEMBL869491 0.90 KDM4E (0.46) KDM4EALDH1A1TDP1PKMMAPT
Acetoacetic Acid SCHEMBL8751811 0.82 KDM4E (0.41) KDM4EALDH1A1TDP1PKMMAPT
Methyl Alcohol SCHEMBL4666816 0.82 KDM4E (0.47) KDM4EALDH1A1TDP1PKMMAPT
SCHEMBL14857813 0.82
SCHEMBL33077 0.82
SCHEMBL1809220 0.82
SCHEMBL9473130 0.82
SCHEMBL20721709 0.82
SCHEMBL1809222 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024138862-A1 COMPOSITION FOR FORMING DIELECTRIC FILM AND USE THEREOF, AND DISPLAY DEVICE 武汉尚赛光电科技有限公司 2024-07-04 WO disclosed
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 EP disclosed
CN-111533668-A Cyanostilbenes 罗利克技术有限公司 2020-08-14 CN disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 US disclosed
CN-105567260-B Functionalized photoreactive compounds 罗利克有限公司 2018-09-11 CN disclosed
WO-2018109469-A1 NOVEL PROCESS ITACONIX (U.K.) LIMITED (GB) 2018-06-21 WO disclosed
EP-3004050-A1 CYANOSTILBENES Rolic AG (CH) 2016-04-13 EP disclosed
US-20160083655-A1 CYANOSTILBENES ROLIC AG (CH) 2016-03-24 US disclosed
WO-2014191292-A1 CYANOSTILBENES ROLIC AG (CH) 2014-12-04 WO disclosed
WO-2013024307-A2 BRANCHED ADDITION COPOLYMERS AND THEIR USE UNILEVER PLC (GB) 2013-02-21 WO disclosed
US-7959990-B2 Adjustment of liquid crystals; oligomers, dendrimers, or polymer in solution is applied to support; crosslinking by radiation or polarized light ROLIC AG (CH) 2011-06-14 US disclosed
EP-1928979-B1 FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS ROLIC AG (CH) 2009-03-04 EP disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 US disclosed
EP-1764405-A1 Functionalized photoreactive compounds Rolic AG (CH) 2007-03-21 EP disclosed
EP-0787154-B1 CONTINUOUS PRODUCTION OF REDUCED GEL CONTENT HYDROXYLATED ADDITION POLYMERS JOHNSON S C COMM MARKETS INC (US) 1999-07-14 EP disclosed
EP-0787154-A1 CONTINUOUS PRODUCTION OF REDUCED GEL CONTENT HYDROXYLATED ADDITION POLYMERS S.C. JOHNSON & SON, INC. (US) 1997-08-06 EP disclosed
WO-1996011957-A1 CONTINUOUS PRODUCTION OF REDUCED GEL CONTENT HYDROXYLATED ADDITION POLYMERS S. C. JOHNSON & SON, INC. (US) 1996-04-25 WO disclosed
US-5508366-A FREE RADICAL ADDITION POLYMERIZATION OF HYDROXY-FUNCTIONAL ETHYNICALLY UNSATURATED MONOMER WITH OTHER COMPATIBLE ADDITION POLYMERIZABLE COPOLYMERS IN A SOLVENT SYSTEM WHICH REDUCES GEL DEPOSIT ON INTERIOR SURFACES OF REACTOR S. C. JOHNSON & SON, INC. (US) 1996-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C KDM4E 2641/4885ALDH1A1 147/4885TDP1 3982/4885
US-20160083655-A1 CYANOSTILBENES LATS1, LATS2, CRY1 KDM4E 1611/4885ALDH1A1 2838/4885TDP1 1993/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 KDM4E 1611/4885ALDH1A1 2838/4885TDP1 1993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.