Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309571 | 0.89 | TACR1 (0.41) | TACR1ADORA2APDE3BPDE3ACCNE1 | |
| SCHEMBL20368043 | 0.86 | TACR1 (0.35) | TACR1ADORA2AMEN1KMT2AALDH1A1 | |
| SCHEMBL12759635 | 0.83 | CCNE1 (0.40) | TACR1ADORA2APDE3BPDE3ACCNE1 | |
| SCHEMBL840594 | 0.79 | RORA (0.38) | TACR1HPGDPTAFRMAPK8 | |
| SCHEMBL839833 | 0.78 | ADORA2A (0.38) | TACR1ADORA2AALDH1A1HPGDPTAFR | |
| SCHEMBL20367998 | 0.78 | TACR1 (0.39) | TACR1ALDH1A1PDE3BPDE3ACCNE1 | |
| SCHEMBL17124141 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ATMKDM4EPDE10AL3MBTL1 | |
| SCHEMBL20368018 | 0.76 | KDM4E (0.39) | TACR1ALDH1A1PTAFRATMMAPK8 | |
| SCHEMBL22262081 | 0.76 | ESR1 (0.39) | TACR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL839608 | 0.76 | ROCK2 (0.36) | TACR1ADORA2APTAFRMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11495751-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-11-08 | — | — | US | disclosed |
| US-20210305518-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-09-30 | — | — | US | disclosed |
| WO-2018127465-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210305518-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | TACR1 2203/4885ADORA2A 3327/4885MEN1 1294/4885 |
| US-11495751-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | TACR1 2203/4885ADORA2A 3327/4885MEN1 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.