Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29745139 | 0.82 | AURKA (0.43) | AURKAAURKBINCENPKDRCDK2 | |
| SCHEMBL7694991 | 0.79 | HDAC6 (0.41) | AURKAAURKBINCENPKDRHDAC1 | |
| SCHEMBL30867600 | 0.76 | ALDH1A1 (0.52) | AURKAAURKBINCENPKDRADORA2A | |
| SCHEMBL86365 | 0.76 | ALDH1A1 (0.52) | AURKAAURKBINCENPKDRADORA2A | |
| SCHEMBL6865280 | 0.76 | AURKA (0.38) | AURKAAURKBINCENPKDRCDK2 | |
| SCHEMBL31408898 | 0.76 | AURKA (0.42) | AURKAAURKBINCENPKDRCDK2 | |
| SCHEMBL15416821 | 0.76 | KDR (0.47) | AURKAAURKBINCENPKDRCDK2 | |
| SCHEMBL5704833 | 0.74 | TSHR (0.41) | AURKAKDRCDK5CDK5R1ADORA2A | |
| SCHEMBL630634 | 0.74 | HDAC6 (0.41) | AURKAAURKBINCENPKDRCDK2 | |
| SCHEMBL21436436 | 0.73 | IDO1 (0.44) | AURKAAURKBINCENPKDRCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180198128-A1 | FLUORINATED-POLYMER COATED ELECTRODES | SOUTH DAKOTA BOARD OF REGENTS (US) | 2018-07-12 | — | — | US | disclosed |