Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30867600 | 1.00 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1IDO1AURKAAURKB | |
| SCHEMBL21436436 | 0.88 | IDO1 (0.44) | ALDH1A1L3MBTL1IDO1AURKAAURKB | |
| SCHEMBL15416821 | 0.83 | KDR (0.47) | AURKAAURKBINCENPKDRADORA2A | |
| SCHEMBL29745139 | 0.83 | AURKA (0.43) | ALDH1A1L3MBTL1IDO1AURKAAURKB | |
| Hydrochloric Acid SCHEMBL15659571 | 0.82 | IDO1 (0.42) | ALDH1A1L3MBTL1IDO1AURKAAURKB | |
| SCHEMBL6865280 | 0.77 | AURKA (0.38) | ALDH1A1IDO1AURKAAURKBINCENP | |
| SCHEMBL7800798 | 0.77 | PDPK1 (0.39) | ALDH1A1L3MBTL1IDO1AURKAAURKB | |
| SCHEMBL20370293 | 0.76 | AURKA (0.39) | AURKAAURKBINCENPKDRADORA2A | |
| Hydrochloric Acid SCHEMBL8099675 | 0.75 | PDPK1 (0.38) | ALDH1A1IDO1AURKAAURKBINCENP | |
| SCHEMBL29079111 | 0.74 | KDR (0.42) | AURKAAURKBKDRADORA2AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117542666-A | Porous ordered graphene/polypyrrole covalent composite supercapacitor electrode material and preparation method and application thereof | 华南理工大学 | 2024-02-09 | — | — | CN | claimed |
| CN-85106344-A | Use contains the imaging system of the photosensitive microcapsules of 4-(4 '-aminophenyl)-pyridine compounds | — | 1987-02-18 | — | — | CN | claimed |
| CN-119390699-A | Synthesis method of pyrrolo [1,2-a ] quinoxaline-4 (5H) -ketone compound | 重庆文理学院 | 2025-02-07 | — | — | CN | disclosed |
| CN-117542666-A | Porous ordered graphene/polypyrrole covalent composite supercapacitor electrode material and preparation method and application thereof | 华南理工大学 | 2024-02-09 | — | — | CN | disclosed |
| WO-2023224560-A1 | ENZYMES AND USES IN BIOCATALYTIC HALOGENATION OF N-HETEROARYLS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2023-11-23 | — | — | WO | disclosed |
| CN-108409743-B | Preparation method of alkyl nitrile substituted pyrrolo [1,2-a ] quinoxaline compound | 兰州大学 | 2021-05-04 | — | — | CN | disclosed |
| EP-3344997-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | Regents of the University of Minnesota (US) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017039778-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20140329866-A1 | OMEGA-CARBOXYARL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS | BAYER HEALTHCARE LLC (US) | 2014-11-06 | — | — | US | disclosed |
| US-8841330-B2 | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors | BAYER HEALTHCARE LLC (US) | 2014-09-23 | — | — | US | disclosed |
| US-20120142742-A1 | OMEGA-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS | BAYER HEALTHERCARE LLC (US) | 2012-06-07 | — | — | US | disclosed |
| US-20010011135-A1 | Omega-carboxyaryl subsituted diphenyl ureas as raf kinase inhibitors | BAYER HEALTHCARE LLC | 2001-08-02 | — | — | US | disclosed |
| US-20010011136-A1 | omega-carboxyyaryl substituted diphenyl ureas as raf kinase inhibitors | BAYER HEALTHCARE LLC | 2001-08-02 | — | — | US | disclosed |
| WO-2000066563-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-11-09 | — | — | WO | disclosed |
| WO-2000041698-A1 | φ-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS p38 KINASE INHIBITORS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |
| WO-2000042012-A1 | φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
| EP-0701428-A1 | AGENTS CONTAINING 1,2-NAPTHOQUINONE FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KGAA (DE) | 1996-03-20 | — | — | EP | disclosed |
| WO-1994028862-A1 | AGENTS CONTAINING 1,2-NAPTHOQUINONE FOR DYEING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010011135-A1 | Omega-carboxyaryl subsituted diphenyl ureas as raf kinase inhibitors | BRAF, RAF1, ARAF | ALDH1A1 1431/4885L3MBTL1 2594/4885IDO1 2131/4885 |
| US-20010011136-A1 | omega-carboxyyaryl substituted diphenyl ureas as raf kinase inhibitors | BRAF, ARAF, RAF1 | ALDH1A1 1887/4885L3MBTL1 2285/4885IDO1 1953/4885 |
| US-20140329866-A1 | OMEGA-CARBOXYARL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS | BRAF, RAF1, ARAF | ALDH1A1 1800/4885L3MBTL1 2098/4885IDO1 2495/4885 |
| US-20120142742-A1 | OMEGA-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS | BRAF, RAF1, ARAF | ALDH1A1 1392/4885L3MBTL1 2791/4885IDO1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.