Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21104351 | 0.85 | P4HTM (0.52) | P4HTMHDAC8 | |
| SCHEMBL18455389 | 0.82 | HDAC1 (0.57) | HDAC1P4HTMHDAC6POLBCA1 | |
| SCHEMBL7278928 | 0.82 | P4HTM (0.65) | HDAC1P4HTMHDAC8HDAC6GRIA4 | |
| SCHEMBL7376125 | 0.81 | P4HTM (0.49) | HDAC1P4HTMGRIA4NR1H4EPHX2 | |
| SCHEMBL15831223 | 0.80 | P4HTM (0.58) | HDAC1P4HTMHDAC8HDAC3HDAC6 | |
| SCHEMBL7990830 | 0.80 | HDAC1 (0.66) | HDAC1P4HTMHDAC8HDAC3HDAC6 | |
| SCHEMBL10116467 | 0.79 | MEN1 (0.62) | HDAC8HDAC3HDAC6HDAC11NR1H4 | |
| SCHEMBL21104540 | 0.78 | CA2 (0.62) | P4HTMCA1CA2KMT2A | |
| SCHEMBL21104541 | 0.78 | FLT1 (0.56) | HDAC1P4HTMHDAC8HDAC3HDAC6 | |
| SCHEMBL20370955 | 0.77 | P4HTM (0.46) | P4HTMNR1H4EPHX2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194799-A1 | BETUIN DERIVATIVES FOR PREVENTING OR TREATING HIV INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194799-A1 | BETUIN DERIVATIVES FOR PREVENTING OR TREATING HIV INFECTIONS | BET1, PGGT1B, RABGGTB | HDAC1 32/4885P4HTM 4597/4885HDAC8 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.