Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373326 | 0.72 | TRPV1 (0.33) | MEN1KMT2AADRB2 | |
| SCHEMBL20357931 | 0.72 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL20357928 | 0.72 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL20357930 | 0.72 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL22839802 | 0.70 | KDM4E (0.40) | MEN1KMT2ALMNAADRB2CHRM3 | |
| SCHEMBL22839848 | 0.70 | ADRB2 (0.36) | ADRB2CHRM3 | |
| SCHEMBL19903848 | 0.70 | CHRM3 (0.42) | ADRB2CHRM3 | |
| SCHEMBL19903850 | 0.70 | CHRM3 (0.39) | ADRB2CHRM3 | |
| SCHEMBL19903846 | 0.68 | ADRB2 (0.36) | MEN1KMT2ALMNAADRB2 | |
| SCHEMBL17978844 | 0.68 | ADRB2 (0.71) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |