Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 10/20 | 0.32 |
| ▸ | DRD2 | P14416 | 6/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373553 | 0.72 | SMN1; SMN2 (0.44) | ADRB2MEN1KMT2A | |
| SCHEMBL20373791 | 0.71 | ADRB2 (0.55) | ADRB2DRD2ADRB1DRD1DRD4 | |
| SCHEMBL19984720 | 0.68 | CHRM3 (0.40) | ADRB2 | |
| SCHEMBL19984506 | 0.67 | ADRB2 (0.43) | ADRB2ADRB1ADRB3 | |
| SCHEMBL21573556 | 0.64 | ADRB2 (0.41) | ADRB2DRD2ADRB1ADRA1DDRD3 | |
| SCHEMBL21573584 | 0.63 | ADRB2 (0.51) | ADRB2KMT2A | |
| SCHEMBL21573521 | 0.60 | KDM4E (0.37) | ADRB2DRD2ADRB1ADRA1D | |
| SCHEMBL21573552 | 0.60 | ADRB2 (0.44) | ADRB2DRD2ADRB1ADRA1D | |
| SCHEMBL19313580 | 0.60 | ALOX15 (0.46) | MEN1KMT2A | |
| SCHEMBL2299425 | 0.56 | TAS1R3 (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |