Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | CTSC | P53634 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16317501 | 0.89 | KDM4E (0.65) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL8699875 | 0.89 | KDM4E (0.69) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL29378473 | 0.89 | KDM4E (0.65) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL18541537 | 0.89 | KDM4E (0.65) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL8699883 | 0.89 | KDM4E (0.69) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL6575986 | 0.88 | KDM4E (0.61) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL7649881 | 0.87 | KDM4E (0.67) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL8424403 | 0.87 | KDM4E (0.67) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL23380924 | 0.86 | POLB (0.66) | KDM4EMAPTMEN1LMNATSHR | |
| SCHEMBL24725504 | 0.85 | KDM4E (0.64) | KDM4EMAPTMEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018127699-A1 | COMPOUNDS FOR TREATING CANCER | Bicyclerd Limited (GB) | 2018-07-12 | — | — | WO | disclosed |