SCHEMBL8699883

SCHEMBL8699883

NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.69
MAPT P10636 2/20 0.69
MEN1 O00255 1/20 0.69
LMNA P02545 1/20 0.69
MPO P05164 1/20 0.69
TSHR P16473 1/20 0.69
BLM P54132 1/20 0.69
PMP22 Q01453 1/20 0.69
KMT2A Q03164 1/20 0.69
HIF1A Q16665 1/20 0.69
HDAC8 Q9BY41 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
NLN Q9BYT8 1/20 0.55
KRAS P01116 1/20 0.55
SOS1 Q07889 1/20 0.55
APAF1 O14727 1/20 0.54
POLB P06746 1/20 0.54
RECQL P46063 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
BCHE P06276 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8699875 1.00 KDM4E (0.69) KDM4EMAPTMEN1LMNAMPO
SCHEMBL7593998 0.95 KDM4E (0.63) KDM4EMAPTMEN1LMNAMPO
SCHEMBL30052868 0.91 KDM4E (0.60) KDM4EMAPTMEN1LMNAMPO
SCHEMBL29378473 0.90 KDM4E (0.65) KDM4EMAPTMEN1LMNAMPO
SCHEMBL18541537 0.90 KDM4E (0.65) KDM4EMAPTMEN1LMNAMPO
SCHEMBL16317501 0.90 KDM4E (0.65) KDM4EMAPTMEN1LMNAMPO
SCHEMBL9868659 0.90 OPRM1 (0.66) KDM4EMAPTMEN1LMNAMPO
SCHEMBL29391520 0.90 OPRM1 (0.66) KDM4EMAPTMEN1LMNAMPO
SCHEMBL31016727 0.89 KDM4E (0.58) KDM4EMAPTMEN1LMNAMPO
SCHEMBL20375720 0.89 KDM4E (0.64) KDM4EMAPTMEN1LMNAMPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4424365-A2 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2024-09-04 EP claimed
EP-4017281-B1 PET FOOD COMPOSITIONS HILLS PET NUTRITION INC (US) 2024-08-28 EP claimed
EP-4017281-A1 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2022-06-29 EP claimed
WO-2021127701-A1 PET FOOD COMPOSITIONS HILL'S PET NUTRITION, INC. (US) 2021-06-24 WO claimed
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 US disclosed
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 US disclosed
EP-3604503-B1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO KK (JP) 2026-03-18 EP disclosed
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF OSPEDALE SAN RAFFAELE S.R.L. (IT) 2026-01-22 US disclosed
US-20250380721-A1 Pet Food Compositions HILL'S PET NUTRITION, INC. (US) 2025-12-18 US disclosed
US-20250295713-A1 COMPOSITIONS AND METHODS FOR IMPROVING SKIN HEALTH AND FOR THE TREATMENT AND PREVENTION OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH PATHOGENIC MICROBES DERMBIONT, INC. 2025-09-25 US disclosed
US-20250270512-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2025-08-28 US disclosed
US-20240390433-A1 GENETICALLY MODIFIED BACILLUS SUBTILIS STRAIN AND USE AS A LIVE DELIVERY AND PRODUCTION SYSTEM BIOMEDIT, INC. 2024-11-28 US disclosed
US-20080267948-A1 Croos-B Structure Binding Compounds CROSSBETA BIOSCIENCES B.V. (NL) 2008-10-30 US disclosed
US-20080267948-A1 Croos-B Structure Binding Compounds CROSSBETA BIOSCIENCES B.V. (NL) 2008-10-30 US disclosed
US-5846942-A Cholecystokinin antagonists, their preparation and therapeutic use WARNER-LAMBERT COMPANY (US) 1998-12-08 US disclosed
US-5593967-A Cholecystokinin antagonists, their preparation and therapeutic use WARNER-LAMBERT COMPANY (US) 1997-01-14 US disclosed
EP-0547178-A4 NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE WARNER LAMBERT CO (US) 1994-07-06 EP disclosed
EP-0547178-A1 NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE WARNER-LAMBERT COMPANY (US) 1993-06-23 EP disclosed
WO-1992004045-A1 NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE WARNER-LAMBERT COMPANY (US) 1992-03-19 WO disclosed
CN-1031025-A NUTRITIVE EMULSION PREPARATION OTSUKA PHARMA CO LTD (JP) 1989-02-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080267948-A1 Croos-B Structure Binding Compounds CACYBP, TBCB, MYCBP KDM4E 4553/4885MAPT 2206/4885MEN1 4546/4885
US-20240390433-A1 GENETICALLY MODIFIED BACILLUS SUBTILIS STRAIN AND USE AS A LIVE DELIVERY AND PRODUCTION SYSTEM BLVRB, GLB1, GUSB KDM4E 4205/4885MAPT 2156/4885MEN1 2725/4885
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES MUC1, VIP, LGALS4 KDM4E 2677/4885MAPT 2398/4885MEN1 2352/4885
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FGF23, FIBP, PTMS KDM4E 3456/4885MAPT 1252/4885MEN1 1814/4885
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF ASNS, AARS1, NARS1 KDM4E 3487/4885MAPT 2780/4885MEN1 4180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.