Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 8/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22268958 | 0.86 | KISS1R (0.34) | FURINKISS1RSIRT5SIRT2GNPAT | |
| SCHEMBL20793386 | 0.86 | KISS1R (0.34) | FURINKISS1RSIRT5SIRT2GNPAT | |
| SCHEMBL22919489 | 0.83 | KISS1R (0.35) | KISS1RNOD1SIRT6SIRT1 | |
| SCHEMBL21781952 | 0.81 | GNPAT (0.35) | FURINKISS1RSIRT5GNPAT | |
| SCHEMBL21103049 | 0.81 | SIRT5 (0.38) | KISS1RSIRT5SIRT2NOD1SIRT6 | |
| SCHEMBL468949 | 0.72 | KISS1R (0.36) | KISS1RNOD1 | |
| SCHEMBL18823532 | 0.71 | DPP4 (0.40) | FURINGNPAT | |
| SCHEMBL677459 | 0.71 | NPY4R (0.46) | SIRT5NOD1 | |
| SCHEMBL25561006 | 0.70 | ECE1 (0.46) | — | |
| SCHEMBL4254687 | 0.70 | ECE1 (0.38) | NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018127699-A1 | COMPOUNDS FOR TREATING CANCER | Bicyclerd Limited (GB) | 2018-07-12 | — | — | WO | disclosed |