Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468949 | 0.87 | KISS1R (0.36) | KISS1RNOD1 | |
| SCHEMBL20375787 | 0.83 | FURIN (0.36) | KISS1RSIRT6SIRT1NOD1 | |
| SCHEMBL22268958 | 0.81 | KISS1R (0.34) | KISS1RSIRT6SIRT1NOD1 | |
| SCHEMBL20793386 | 0.81 | KISS1R (0.34) | KISS1RSIRT6SIRT1NOD1 | |
| SCHEMBL12890790 | 0.79 | KISS1R (0.53) | KISS1R | |
| SCHEMBL13366903 | 0.79 | KISS1R (0.53) | KISS1R | |
| SCHEMBL14525182 | 0.79 | KISS1R (0.53) | KISS1R | |
| SCHEMBL21781952 | 0.79 | GNPAT (0.35) | KISS1R | |
| SCHEMBL23743653 | 0.76 | KISS1R (0.36) | KISS1RSIRT6SIRT1 | |
| SCHEMBL14951121 | 0.76 | NOD1 (0.32) | NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3769776-A1 | PEPTIDOMIMETIC MACROCYCLES | Aileron Therapeutics, Inc. (US) | 2021-01-27 | — | — | EP | disclosed |