Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16890212 | 0.88 | KDM4E (0.53) | L3MBTL1KDM4EATMALDH1A1PPARG | |
| SCHEMBL13957097 | 0.85 | KDM4E (0.57) | L3MBTL1KDM4EATMALDH1A1HTT | |
| SCHEMBL4402485 | 0.85 | KDM4E (0.57) | L3MBTL1KDM4EATMALDH1A1HTT | |
| SCHEMBL4251517 | 0.85 | KDM4E (0.57) | L3MBTL1KDM4EATMALDH1A1HTT | |
| SCHEMBL21969436 | 0.85 | KDM4E (0.49) | L3MBTL1KDM4EATMALDH1A1PPARG | |
| SCHEMBL680510 | 0.83 | KDM4E (0.55) | L3MBTL1KDM4EATMALDH1A1HTT | |
| SCHEMBL16890387 | 0.82 | KDM4E (0.52) | L3MBTL1KDM4EATMALDH1A1PPARG | |
| SCHEMBL24031766 | 0.81 | KDM4E (0.37) | L3MBTL1KDM4EATMALDH1A1PPARG | |
| SCHEMBL4256758 | 0.81 | KDM4E (0.52) | L3MBTL1KDM4EATMALDH1A1HTT | |
| SCHEMBL3779321 | 0.81 | KDM4E (0.52) | L3MBTL1KDM4EATMALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345911-A1 | POLYCYCLIC AROMATIC COMPOUNDS AND THEIR USE AS ORGANIC DEVICE MATERIAL | Kwansei Gakuin Educational Foundation (JP) | 2018-07-11 | — | — | EP | disclosed |