SCHEMBL3779321

SCHEMBL3779321

Cc1ccc2c(c1)c1ccccc1n2-c1ccc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ATM Q13315 1/20 0.52
AKR1C4 P17516 1/20 0.42
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
HDAC4 P56524 1/20 0.42
MAPT P10636 3/20 0.40
HTT P42858 3/20 0.40
BCHE P06276 1/20 0.40
ACHE P22303 1/20 0.40
LMNA P02545 1/20 0.40
PGR P06401 1/20 0.39
RORA P35398 1/20 0.39
RORC P51449 1/20 0.39
RORB Q92753 1/20 0.39
ALDH1A1 P00352 5/20 0.38
PTGER4 P35408 1/20 0.37
MEN1 O00255 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1322395 1.00 KDM4E (0.52) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL12454703 1.00 KDM4E (0.52) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL26226576 0.97 KDM4E (0.48) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL14079144 0.97 KDM4E (0.48) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL12109712 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL23679400 0.97 KDM4E (0.53) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL14079149 0.97 KDM4E (0.48) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL4402485 0.95 KDM4E (0.57) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL4251517 0.95 KDM4E (0.57) KDM4EL3MBTL1ATMAKR1C4AKR1C3
SCHEMBL13957097 0.95 KDM4E (0.57) KDM4EL3MBTL1ATMAKR1C4AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3081617-B1 BLUE EMITTER WITH HIGH EFFICIENCY BASED ON IMIDAZO [1,2-F] PHENANTHRIDINE IRIDIUM COMPLEXES UNIVERSAL DISPLAY CORP (US) 2017-11-15 EP disclosed
US-8546505-B2 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2013-10-01 US disclosed
US-8334527-B2 Electroluminescent device DAI NIPPON PRINTING CO., LTD. (JP) 2012-12-18 US disclosed
US-8043793-B2 Method for manufacturing electroluminescence element DAI NIPPON PRINTING CO., LTD. (JP) 2011-10-25 US disclosed
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials GEORGIA TECH RESEARCH CORPORATION (US) 2010-12-30 US disclosed
US-20100224856-A1 ELECTROLUMINESCENT DEVICE DAI NIPPON PRINTING CO., LTD 2010-09-09 US disclosed
US-20090184292-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-23 US disclosed
US-20090153021-A1 LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS WASHINGTON, UNIVERSITY OF (US) 2009-06-18 US disclosed
US-20090153021-A1 LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS WASHINGTON, UNIVERSITY OF (US) 2009-06-18 US disclosed
US-20090085473-A1 ELECTROLUMINESCENT ELEMENT AND MANUFACTURING METHOD THEREOF DAI NIPPON PRINTING CO., LTD. (JP) 2009-04-02 US disclosed
US-20090087792-A1 METHOD FOR MANUFACTURING ELECTROLUMINESCENCE ELEMENT DAI NIPPON PRINTIG CO., LTD. (JP) 2009-04-02 US disclosed
WO-2007133632-A2 LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS UNIVERSITY OF WASHINGTON (US) 2007-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090153021-A1 LARGE-BANDGAP HOST MATERIALS FOR PHOSPHORESCENT EMITTERS IQGAP1, SGTA, DPAGT1 KDM4E 2906/4885L3MBTL1 2082/4885ATM 3252/4885
US-20100331509-A1 Carbazole-based hole transport and/or electron blocking materials and/or host polymer materials OCIAD1, HPD, OXA1L KDM4E 4260/4885L3MBTL1 1007/4885ATM 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.