Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12327196 | 0.79 | GLA (0.43) | LIPCLIPGPTGER4BACE1BACE2 | |
| SCHEMBL739595 | 0.76 | NPC1 (0.43) | SOS1CNR2CNR1KDM4C | |
| SCHEMBL21324939 | 0.76 | LIPC (0.45) | LIPCLIPGPTGER4BACE1BACE2 | |
| SCHEMBL21536701 | 0.76 | BACE1 (0.37) | LIPCLIPGPTGER4BACE1BACE2 | |
| SCHEMBL20376206 | 0.74 | CYP3A4 (0.36) | — | |
| SCHEMBL20376237 | 0.71 | IDO1 (0.35) | KDM4C | |
| SCHEMBL25039614 | 0.70 | TRPV4 (0.43) | — | |
| SCHEMBL21695734 | 0.70 | CNR2 (0.49) | CNR2KDM1AMAPK14 | |
| SCHEMBL17064891 | 0.69 | KLKB1 (0.50) | SOS1 | |
| SCHEMBL17073530 | 0.69 | KLKB1 (0.50) | SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |