Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207665 | 0.85 | HRH3 (0.33) | NOS3NOS1NOS2IDO1HRH3 | |
| SCHEMBL12336888 | 0.74 | HRH3 (0.40) | NOS3NOS1NOS2HRH3CYP1A2 | |
| SCHEMBL19608193 | 0.74 | CCR1 (0.44) | NOS3NOS1NOS2 | |
| SCHEMBL18929523 | 0.73 | HRH3 (0.33) | NOS3NOS1NOS2HRH3CYP1A2 | |
| SCHEMBL16180534 | 0.72 | GBA1 (0.46) | NOS3NOS1NOS2 | |
| SCHEMBL14950464 | 0.72 | IDO1 (0.52) | NOS1IDO1 | |
| SCHEMBL14389059 | 0.69 | HRH3 (0.50) | IDO1HRH3CYP1A2CYP2D6 | |
| SCHEMBL25921510 | 0.69 | NOS3 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL19708881 | 0.69 | MAPT (0.33) | NOS3NOS1NOS2IDO1HRH3 | |
| SCHEMBL19608557 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |