Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20376261 | 0.85 | NOS3 (0.36) | HRH3NOS3NOS1NOS2CYP1A2 | |
| SCHEMBL12336888 | 0.82 | HRH3 (0.40) | HRH3NOS3NOS1NOS2CYP1A2 | |
| SCHEMBL18929523 | 0.81 | HRH3 (0.33) | HRH3NOS3NOS1NOS2CYP1A2 | |
| SCHEMBL14389059 | 0.78 | HRH3 (0.50) | HRH3CYP1A2CYP2D6IDO1 | |
| SCHEMBL19708881 | 0.77 | MAPT (0.33) | HRH3NOS3NOS1NOS2IDO1 | |
| SCHEMBL26687370 | 0.75 | HSP90AB1 (0.39) | HRH3CYP1A2CYP2D6 | |
| SCHEMBL9610886 | 0.74 | SMN1; SMN2 (0.45) | CYP1A2 | |
| SCHEMBL23478964 | 0.72 | GABRP (0.48) | NOS3NOS1NOS2 | |
| SCHEMBL30185830 | 0.72 | ALDH1A1 (0.47) | — | |
| SCHEMBL1146035 | 0.72 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |