Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17752772 | 0.93 | IDO1 (0.46) | IDO1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5209430 | 0.86 | MAPT (0.44) | IDO1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21765871 | 0.78 | HRH3 (0.42) | IDO1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17752834 | 0.78 | IDO1 (0.50) | IDO1NOS1 | |
| SCHEMBL14099205 | 0.77 | FOLH1 (0.42) | IDO1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL127369 | 0.76 | IDO1 (0.69) | IDO1 | |
| SCHEMBL515186 | 0.76 | MAPT (0.56) | IDO1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10299392 | 0.76 | IDO1 (0.52) | IDO1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21134934 | 0.75 | IDO1 (0.48) | IDO1NOS1 | |
| SCHEMBL7658349 | 0.74 | TRPA1 (0.43) | IDO1MAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123458-A1 | CATALYTIC POLYMERIZATION OF POLYMERS CONTAINING ELECTROPHIIC LINKAGES USING NUCLEOPHILIC REAGENTS | THE BOARD OF DIRECTORS OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-05-16 | — | — | US | disclosed |