Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377178 | 1.00 | INSR (0.34) | INSRGHSRCA12CA1CA2 | |
| SCHEMBL20377179 | 0.91 | CA12 (0.33) | INSRCA12CA1CA2CA9 | |
| SCHEMBL20377177 | 0.91 | CA12 (0.33) | INSRCA12CA1CA2CA9 | |
| SCHEMBL20377163 | 0.88 | MAPT (0.41) | INSRCA12CA1CA2CA9 | |
| SCHEMBL20377164 | 0.88 | MAPT (0.41) | INSRCA12CA1CA2CA9 | |
| SCHEMBL20377114 | 0.83 | RIPK1 (0.35) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL821710 | 0.83 | RIPK1 (0.35) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL20377174 | 0.81 | INSR (0.39) | INSRKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL821431 | 0.81 | INSR (0.39) | INSRKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL821342 | 0.76 | KDR (0.49) | KDM4ESMN1; SMN2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | claimed |