Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HK1 | P19367 | 2/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20378953 | 0.81 | MAPT (0.51) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL20378948 | 0.81 | RAB9A (0.49) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| Bromide SCHEMBL7464206 | 0.80 | NPC1 (0.55) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| Bromide SCHEMBL7477025 | 0.80 | MAPT (0.55) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL20378791 | 0.77 | NPC1 (0.49) | MAPTSMN1; SMN2NPC1RAB9AGAA | |
| Bromide SCHEMBL20378968 | 0.77 | RAB9A (0.49) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL20379019 | 0.74 | MAPT (0.56) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL18388773 | 0.74 | MAPT (0.46) | MAPTSMN1; SMN2NPC1RAB9ACYP3A4 | |
| SCHEMBL18388738 | 0.73 | SMN1; SMN2 (0.55) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5567189 | 0.71 | KDM4E (0.39) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180201592-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | F2G LIMITED (GB) | 2018-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180201592-A1 | 2-AMINO-1,3,4-THIADIAZINE AND 2-AMINO-1,3,4-OXADIAZINE BASED ANTIFUNGAL AGENTS | NAT1, DPM1, IL4I1 | MAPT 103/4885SMN1; SMN2 2798/4885NPC1 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.