Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.43 |
| ▸ | FGF1 | P05230 | 3/20 | 0.43 |
| ▸ | FGF2 | P09038 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785542 | 0.92 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL21762380 | 0.92 | CYP3A4 (0.53) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL28380135 | 0.92 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL22525087 | 0.92 | CYP3A4 (0.53) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL21762057 | 0.92 | CYP3A4 (0.53) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL16217958 | 0.92 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL22952982 | 0.92 | CYP3A4 (0.53) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL22380806 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL22688576 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL18929669 | 0.91 | CYP3A4 (0.50) | CYP3A4MAPTCYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023861-B2 | Oligomer-conjugate complexes and their use | IONIS PHARMACEUTICALS, INC. (US) | 2018-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023861-B2 | Oligomer-conjugate complexes and their use | DCLRE1B, NT5C3B, PAICS | CYP3A4 4548/4885MAPT 1258/4885CYP2C9 4036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.