Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.38 |
| ▸ | FGF1 | P05230 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21762380 | 1.00 | CYP3A4 (0.53) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL22525087 | 1.00 | CYP3A4 (0.53) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL22952982 | 1.00 | CYP3A4 (0.53) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL25042624 | 0.97 | CYP3A4 (0.52) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL20827903 | 0.97 | CYP3A4 (0.52) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL25098567 | 0.97 | CYP3A4 (0.52) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL22504902 | 0.97 | CYP3A4 (0.54) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL23573731 | 0.95 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL28380135 | 0.93 | CYP3A4 (0.51) | CYP3A4MAPTCYP2C9CYP2C19LMNA | |
| SCHEMBL20577441 | 0.92 | CYP3A4 (0.48) | CYP3A4MAPTCYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355775-A1 | NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING SAME, PREPARATION METHOD, AND USE THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230132756-A1 | DOUBLE-STRANDED OLIGONUCLEOTIDE, COMPOSITION AND CONJUGATE COMPRISING DOUBLE-STRANDED OLIGONUCLEOTIDE, PREPARATION METHOD THEREOF AND USE THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20220389428-A1 | NUCLEIC ACID, COMPOSITION AND CONJUGATE COMPRISING THE SAME, AND PREPARATION METHOD AND USE THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2022-12-08 | — | — | US | disclosed |
| US-20210277400-A1 | NUCLEIC ACID, COMPOSITION AND CONJUGATE COMPRISING THE SAME, AND PREPARATION METHOD AND USE THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2021-09-09 | — | — | US | disclosed |
| EP-3842534-A1 | NUCLEIC ACID, PHARMACEUTICAL COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, AND USE THEREOF | Suzhou Ribo Life Science Co., Ltd. (CN) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020038377-A1 | NUCLEIC ACID, PHARMACEUTICAL COMPOSITION AND CONJUGATE CONTAINING NUCLEIC ACID, AND USE THEREOF | 苏州瑞博生物技术有限公司 | 2020-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210277400-A1 | NUCLEIC ACID, COMPOSITION AND CONJUGATE COMPRISING THE SAME, AND PREPARATION METHOD AND USE THEREOF | NSUN2, RNGTT, ADAR | CYP3A4 3271/4885MAPT 2616/4885CYP2C9 2319/4885 |
| US-20220389428-A1 | NUCLEIC ACID, COMPOSITION AND CONJUGATE COMPRISING THE SAME, AND PREPARATION METHOD AND USE THEREOF | NSUN2, RNGTT, ADAR | CYP3A4 3271/4885MAPT 2616/4885CYP2C9 2319/4885 |
| US-20230355775-A1 | NUCLEIC ACID, COMPOSITION AND CONJUGATE CONTAINING SAME, PREPARATION METHOD, AND USE THEREOF | APOB, C1QBP, APOL1 | CYP3A4 3320/4885MAPT 2773/4885CYP2C9 2580/4885 |
| US-20230132756-A1 | DOUBLE-STRANDED OLIGONUCLEOTIDE, COMPOSITION AND CONJUGATE COMPRISING DOUBLE-STRANDED OLIGONUCLEOTIDE, PREPARATION METHOD THEREOF AND USE THEREOF | POLN, POLM, DUT | CYP3A4 2969/4885MAPT 3127/4885CYP2C9 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.