Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 10/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978905 | 0.84 | HRH1 (0.54) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL20978787 | 0.83 | HRH1 (0.53) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL20381716 | 0.82 | HRH1 (0.54) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL14474308 | 0.79 | HRH1 (0.63) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL12909408 | 0.79 | HRH1 (0.72) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL20978788 | 0.73 | HRH1 (0.52) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL10846771 | 0.73 | HRH1 (0.57) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL14475370 | 0.72 | DRD3 (0.63) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL14475369 | 0.72 | HRH1 (0.49) | HRH1HRH4DRD3LMNACHRM2 | |
| SCHEMBL9333208 | 0.71 | HRH1 (0.44) | HRH1HRH4FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10022362-B2 | Anti-allergy benzocycloheptathiophene derivatives | FUJIAN MINDONG REJUVENATION PHARMACEUTICAL CO., LTD (CN) | 2018-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10022362-B2 | Anti-allergy benzocycloheptathiophene derivatives | NR1H4, TST, CYP7A1 | HRH1 14/4885HRH4 11/4885DRD3 2282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.