Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333178 | 0.86 | FNTA (0.46) | HRH1HRH3ROCK2MGLLALDH1A1 | |
| SCHEMBL9332847 | 0.85 | DRD3 (0.51) | HRH1HRH4HRH3ROCK2ALDH1A1 | |
| SCHEMBL9380680 | 0.80 | PTAFR (0.55) | HRH1FNTAFNTB | |
| SCHEMBL20978788 | 0.78 | HRH1 (0.52) | HRH1HRH4HPGDHTTFNTA | |
| SCHEMBL9332709 | 0.76 | FNTA (0.63) | HRH1FNTAFNTB | |
| SCHEMBL9332755 | 0.76 | FNTA (0.63) | HRH1FNTAFNTB | |
| SCHEMBL9333282 | 0.74 | PTAFR (0.59) | HRH1MGLLFNTAFNTB | |
| SCHEMBL9332876 | 0.73 | FNTA (0.65) | HRH1FNTAFNTB | |
| SCHEMBL20381726 | 0.71 | HRH1 (0.54) | HRH1HRH4FNTAFNTB | |
| SCHEMBL9333210 | 0.71 | FNTA (0.52) | HRH1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358953-A | For treatment of allergic rhinitis | PFIZER INC. (US) | 1994-10-25 | — | — | US | disclosed |