Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.57 |
| ▸ | BCHE | P06276 | 3/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | WEE1 | P30291 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355218 | 0.91 | BCHE (0.53) | ACHEBCHEALOX5PTGS1PTGS2 | |
| SCHEMBL11808516 | 0.89 | BCHE (0.67) | ACHEBCHEALOX5PTGS1PTGS2 | |
| SCHEMBL793546 | 0.87 | BCHE (0.56) | ACHEBCHEMAPTMEN1NR1I2 | |
| SCHEMBL6940359 | 0.83 | BCHE (0.53) | ACHEBCHEMAPTMEN1NR1I2 | |
| SCHEMBL27985040 | 0.80 | GPR3 (0.64) | ACHEBCHEALOX5PTGS1PTGS2 | |
| SCHEMBL21093610 | 0.79 | POLB (0.40) | ACHEBCHEALOX5PTGS1PTGS2 | |
| SCHEMBL21093609 | 0.79 | KDM4E (0.46) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20466817 | 0.79 | BCHE (0.54) | ACHEBCHEMAPTMEN1NR1I2 | |
| SCHEMBL11998153 | 0.79 | BCHE (0.50) | ACHEBCHEMAPTMEN1NR1I2 | |
| SCHEMBL14900745 | 0.79 | BCHE (0.50) | ACHEBCHEMAPTMEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252624-B1 | ELECTROLUMINESCENT METAL COMPLEXES WITH DIBENZO[F,H]QUINOXALINES | UDC IRELAND LTD (IE) | 2018-07-18 | — | — | EP | disclosed |