Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 2/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | WEE1 | P30291 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985040 | 0.89 | GPR3 (0.64) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL20384979 | 0.89 | ACHE (0.57) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL14050151 | 0.88 | BCHE (0.56) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL3874806 | 0.88 | BCHE (0.56) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL12926001 | 0.81 | MAPT (0.53) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL12355218 | 0.80 | BCHE (0.53) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL3886263 | 0.80 | BCHE (0.52) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL11378517 | 0.79 | HTT (0.57) | BCHEACHEWEE1KDM4EALDH1A1 | |
| SCHEMBL1929490 | 0.79 | ACHE (0.51) | BCHEACHEALOX5PTGS1PTGS2 | |
| SCHEMBL17928546 | 0.78 | BCHE (0.46) | BCHEACHEALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947593-A | ANTIVIRUL AGENTS | RICHARDSON-MERRELL INC. (US) | 1976-03-30 | — | — | US | disclosed |
| US-3932424-A | Bis-basic ethers of carbazole | RICHARDSON-MERRELL INC. (US) | 1976-01-13 | — | — | US | disclosed |