Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385122 | 0.82 | HTT (0.41) | ALDH1A1LMNARAB9ANPC1MEN1 | |
| SCHEMBL20385172 | 0.82 | CYP1A2 (0.50) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL20385119 | 0.79 | CYP1A2 (0.47) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL20385118 | 0.75 | ALDH1A1 (0.48) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL16919734 | 0.74 | CYP1A2 (0.77) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL20385120 | 0.70 | ALDH1A1 (0.48) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL31680566 | 0.67 | CYP1A2 (0.89) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL20385168 | 0.64 | SIGMAR1 (0.40) | KDM4EALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL20385134 | 0.64 | POLB (0.43) | CYP1A2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL20385093 | 0.63 | HDAC1 (0.41) | KDM4ERAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |