Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385125 | 0.85 | HPGD (0.50) | HTTHPGDKMT2AALDH1A1NPC1 | |
| SCHEMBL20385152 | 0.83 | HTT (0.47) | HTTPOLBKMT2AALDH1A1NPC1 | |
| SCHEMBL20385146 | 0.82 | KMT2A (0.40) | HTTKCNN4HPGDPOLBRXFP1 | |
| SCHEMBL20385151 | 0.81 | HTT (0.41) | HTTPOLBKMT2AALDH1A1NPC1 | |
| SCHEMBL20385162 | 0.80 | KCNN4 (0.40) | HTTDHODHKCNN4HPGDPOLB | |
| SCHEMBL20385115 | 0.79 | HTT (0.43) | HTTPOLBKMT2AALDH1A1NPC1 | |
| SCHEMBL20385135 | 0.79 | NPC1 (0.44) | HTTPOLBKMT2ANPC1RAB9A | |
| SCHEMBL20385145 | 0.79 | KCNN4 (0.41) | HTTKCNN4HPGDSCN9APOLB | |
| SCHEMBL20385136 | 0.78 | MRGPRX1 (0.43) | HTTKCNN4KMT2AALDH1A1RAB9A | |
| SCHEMBL20385157 | 0.78 | NPC1 (0.40) | HTTDHODHPOLBRXFP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |