Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385162 | 0.84 | KCNN4 (0.40) | NPC1HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20385125 | 0.83 | HPGD (0.50) | NPC1HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20385145 | 0.81 | KCNN4 (0.41) | NPC1HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20385136 | 0.80 | MRGPRX1 (0.43) | HTTKMT2AALDH1A1GAARAB9A | |
| SCHEMBL20385159 | 0.80 | KCNN4 (0.45) | NPC1HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20385146 | 0.80 | KMT2A (0.40) | HTTL3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL20385086 | 0.80 | KCNN4 (0.43) | NPC1HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20385126 | 0.78 | HTT (0.39) | NPC1HTTKMT2AALDH1A1RAB9A | |
| SCHEMBL20385152 | 0.78 | HTT (0.47) | NPC1HTTKMT2AALDH1A1MEN1 | |
| SCHEMBL20385121 | 0.78 | HTT (0.43) | NPC1HTTL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |