Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385162 | 0.82 | KCNN4 (0.40) | KCNN4ALDH1A1HTTKMT2AGAA | |
| SCHEMBL20385145 | 0.81 | KCNN4 (0.41) | KCNN4ALDH1A1HTTKMT2AFEN1 | |
| SCHEMBL20385157 | 0.80 | NPC1 (0.40) | ALDH1A1HTTKMT2AGAARAB9A | |
| SCHEMBL20385125 | 0.80 | HPGD (0.50) | ALDH1A1HTTKMT2AGAARAB9A | |
| SCHEMBL20385126 | 0.78 | HTT (0.39) | KCNN4ALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL20385152 | 0.78 | HTT (0.47) | ALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL20385146 | 0.77 | KMT2A (0.40) | MRGPRX1KCNN4ALDH1A1HTTKMT2A | |
| SCHEMBL20385115 | 0.75 | HTT (0.43) | ALDH1A1HTTKMT2ARAB9A | |
| SCHEMBL20385135 | 0.75 | NPC1 (0.44) | HTTKMT2AGAARAB9A | |
| SCHEMBL20385150 | 0.74 | ALDH1A1 (0.38) | KCNN4ALDH1A1HTTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |