Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385159 | 0.90 | KCNN4 (0.45) | KCNN4HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL20385150 | 0.87 | ALDH1A1 (0.38) | KCNN4HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL20385143 | 0.84 | KCNN4 (0.41) | KCNN4HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL20385149 | 0.83 | ALDH1A1 (0.38) | HTTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20385147 | 0.82 | HPGD (0.48) | HTTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20385148 | 0.80 | HTT (0.44) | HTTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20385157 | 0.80 | NPC1 (0.40) | HTTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20385085 | 0.77 | HTT (0.42) | HTTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20385160 | 0.76 | HTT (0.41) | HTTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL20385132 | 0.75 | HPGD (0.48) | HTTKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |