Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385173 | 0.88 | NPC1 (0.47) | CLCN2POLBNPC1CASP3ATM | |
| SCHEMBL20385139 | 0.86 | HDAC1 (0.42) | CLCN2HPGDALDH1A1GAAHSD17B10 | |
| SCHEMBL20385147 | 0.85 | HPGD (0.48) | NPC1CASP3ATMSENP7HPGD | |
| SCHEMBL20385165 | 0.82 | HPGD (0.42) | POLBHPGDALDH1A1GAARAB9A | |
| SCHEMBL20385084 | 0.81 | KDM4E (0.40) | NPC1HPGDALDH1A1GAARAB9A | |
| SCHEMBL20385132 | 0.81 | HPGD (0.48) | NPC1ATMHPGDALDH1A1HSD17B10 | |
| SCHEMBL20385116 | 0.77 | GRIN2D (0.47) | POLBHPGDALDH1A1GAAHSD17B10 | |
| SCHEMBL20385160 | 0.76 | HTT (0.41) | POLBNPC1HPGDALDH1A1GAA | |
| SCHEMBL20385119 | 0.75 | CYP1A2 (0.47) | NPC1ATMHPGDALDH1A1L3MBTL1 | |
| SCHEMBL20385111 | 0.74 | KMT2A (0.48) | POLBNPC1HPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |