Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20385132 | 0.90 | HPGD (0.48) | HPGDKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL20385139 | 0.89 | HDAC1 (0.42) | HPGDKDM4EALDH1A1MAPTTP53 | |
| SCHEMBL20385125 | 0.88 | HPGD (0.50) | HPGDKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL20385150 | 0.86 | ALDH1A1 (0.38) | HPGDKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL20385148 | 0.86 | HTT (0.44) | KDM4EALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20385171 | 0.85 | CLCN2 (0.43) | HPGDKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL20385159 | 0.85 | KCNN4 (0.45) | KDM4ELMNAALDH1A1RAB9AMAPT | |
| SCHEMBL20385165 | 0.85 | HPGD (0.42) | HPGDALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL20385149 | 0.84 | ALDH1A1 (0.38) | HPGDKDM4ELMNAALDH1A1RAB9A | |
| SCHEMBL20385143 | 0.83 | KCNN4 (0.41) | HPGDKDM4ELMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867215-B1 | TETRAZOLE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | SANIONA AS (DK) | 2018-07-18 | — | — | EP | disclosed |