Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2036249 | 0.81 | LMNA (0.45) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL28320576 | 0.80 | LMNA (0.54) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL2038667 | 0.75 | LMNA (0.49) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL289027 | 0.73 | LMNA (0.59) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL15145284 | 0.73 | LMNA (0.59) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL2036126 | 0.71 | LMNA (0.51) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL12803722 | 0.71 | LMNA (0.51) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL30664028 | 0.70 | LMNA (0.46) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL28613482 | 0.70 | LMNA (0.46) | LMNAERN1POLBPRKDCALDH1A1 | |
| SCHEMBL2042115 | 0.69 | LMNA (0.66) | LMNAERN1POLBPRKDCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8525131-B2 | Phosphorescent organic compounds | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-09-03 | — | — | US | claimed |
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-04 | — | — | US | claimed |
| WO-2011066415-A2 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-06-03 | — | — | WO | claimed |
| US-8525131-B2 | Phosphorescent organic compounds | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-09-03 | — | — | US | disclosed |
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-04 | — | — | US | disclosed |
| WO-2011066415-A2 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | PAICS, PPIP5K2, PPA1 | LMNA 3394/4885ERN1 2666/4885POLB 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.