Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19450501 | 0.92 | EPHX1 (0.39) | NOS3NOS1NOS2HDAC3HDAC4 | |
| SCHEMBL35715 | 0.81 | NOS3 (0.50) | NOS3NOS1NOS2LMNAHTT | |
| SCHEMBL180793 | 0.79 | EPHX1 (0.36) | NOS3NOS1NOS2LMNAHTT | |
| SCHEMBL4245291 | 0.79 | NOS3 (0.34) | NOS3NOS1NOS2 | |
| SCHEMBL3088096 | 0.77 | EPHX1 (0.50) | NOS3NOS1NOS2LMNAHTT | |
| SCHEMBL14102731 | 0.77 | — | — | |
| SCHEMBL22657366 | 0.77 | NOS3 (0.46) | NOS3NOS1NOS2LMNAHTT | |
| SCHEMBL3714955 | 0.75 | CA1 (0.39) | NOS3NOS1NOS2HDAC2LMNA | |
| SCHEMBL18217958 | 0.75 | — | — | |
| SCHEMBL1441085 | 0.75 | NOS3 (0.44) | NOS3NOS1NOS2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1463765-B1 | AQUEOUS DISPERSIONS OF POLYMER PARTICLES | UNIV SYDNEY (AU) | 2018-07-18 | — | — | EP | disclosed |