SCHEMBL4245291

SCHEMBL4245291

CCCCSC(=S)SC(C)C#N

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16405442 0.93 EPHX1 (0.34)
SCHEMBL22198517 0.81
SCHEMBL20387804 0.79 NOS3 (0.40) NOS3NOS1NOS2
SCHEMBL14102733 0.76 TSHR (0.35) TSHR
SCHEMBL16852235 0.75 EPHX1 (0.30)
SCHEMBL21465717 0.73 EPHX1 (0.33) TSHR
SCHEMBL35715 0.73 NOS3 (0.50) NOS3NOS1NOS2TSHR
SCHEMBL27130884 0.72
SCHEMBL19450501 0.72 EPHX1 (0.39) NOS3NOS1NOS2TSHR
SCHEMBL180793 0.71 EPHX1 (0.36) NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009121148-A1 DYE COMPRISING FUNCTIONAL SUBSTITUENT ADVANCED POLYMERIK PTY LTD (AU) 2009-10-08 WO disclosed