Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21440817 | 0.97 | MEN1 (0.45) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL21440836 | 0.97 | MEN1 (0.45) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL22764284 | 0.88 | TSHR (0.40) | MEN1KMT2ACES2FAAHTSHR | |
| SCHEMBL23874288 | 0.87 | GLP1R (0.40) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL22909210 | 0.87 | KDM4E (0.44) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL27408418 | 0.87 | KDM4E (0.44) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL16327984 | 0.87 | KDM4E (0.44) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL21106914 | 0.87 | KDM4E (0.44) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL21501611 | 0.86 | CES2 (0.38) | MEN1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL16882443 | 0.84 | MEN1 (0.41) | MEN1KMT2AKDM4ETDP1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643023-B1 | RADIOIODINATION METHOD | GE HEALTHCARE LTD (GB) | 2018-07-18 | — | — | EP | disclosed |