Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26020310 | 0.97 | MEN1 (0.41) | GLP1RMEN1KMT2ATSHRCES2 | |
| SCHEMBL21440817 | 0.90 | MEN1 (0.45) | GLP1RMEN1KMT2ACES2KDM4E | |
| SCHEMBL21440836 | 0.90 | MEN1 (0.45) | GLP1RMEN1KMT2ACES2KDM4E | |
| SCHEMBL21501611 | 0.89 | CES2 (0.38) | GLP1RMEN1KMT2ATSHRCES2 | |
| SCHEMBL21925758 | 0.88 | GLP1R (0.39) | GLP1RMEN1KMT2ATSHRKDM4E | |
| SCHEMBL20388153 | 0.87 | MEN1 (0.45) | GLP1RMEN1KMT2ATSHRCES2 | |
| SCHEMBL12147645 | 0.87 | TSHR (0.47) | GLP1RMEN1KMT2ATSHRCES2 | |
| SCHEMBL26865995 | 0.85 | MEN1 (0.41) | GLP1RMEN1KMT2ATSHRKDM4E | |
| SCHEMBL26866021 | 0.85 | GLP1R (0.48) | GLP1RMEN1KMT2ATSHRPOLB | |
| SCHEMBL22764284 | 0.85 | TSHR (0.40) | MEN1KMT2ATSHRCES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021193984-A2 | QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-09-30 | — | — | WO | disclosed |