Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040436 | 0.86 | MAPT (0.58) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2041310 | 0.83 | HPGD (0.59) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2037438 | 0.77 | MAPT (0.61) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2040082 | 0.77 | KDM4E (0.56) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2037443 | 0.74 | MAPT (0.64) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2044273 | 0.74 | NOX4 (0.49) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2036868 | 0.72 | MAPT (0.59) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL27912688 | 0.72 | MAPT (0.66) | KDM4ERAB9ASMN1; SMN2HPGDLMNA | |
| SCHEMBL2044582 | 0.72 | MAPT (0.57) | KDM4ENPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL2039170 | 0.72 | MAPT (0.61) | KDM4ENPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120753-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-09-01 | — | — | US | claimed |
| US-20130172564-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-04 | — | — | US | claimed |
| EP-2516399-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | claimed |
| WO-2011077044-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | claimed |
| EP-2516399-B1 | PHENOLIC DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RES & DEV (FR) | 2018-04-18 | — | — | EP | disclosed |
| US-9120753-B2 | Phenol derivatives and pharmaceutical or cosmetic use thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-09-01 | — | — | US | disclosed |
| US-20130172564-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-07-04 | — | — | US | disclosed |
| EP-2516399-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | Galderma Research & Development (FR) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011077044-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172564-A1 | PHENOL DERIVATIVES AND PHARMACEUTICAL OR COSMETIC USE THEREOF | TYR, MITF, CUTA | KDM4E 1468/4885NPC1 1183/4885RAB9A 2918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.