Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393708 | 0.92 | PTGS2 (0.40) | NLRP3PTGER4DHODHLMNASMN1; SMN2 | |
| SCHEMBL20393714 | 0.91 | PTGS2 (0.38) | PTGER4LMNAHTTSMN1; SMN2PTGS2 | |
| SCHEMBL20393715 | 0.87 | RORC (0.36) | PTGER4DHODHPTGS2S1PR1ACSS2 | |
| SCHEMBL21715798 | 0.85 | LMNA (0.37) | PTGER4LMNAHTTSMN1; SMN2PTGS2 | |
| SCHEMBL21715796 | 0.85 | LMNA (0.36) | PTGER4LMNAHTTSMN1; SMN2S1PR1 | |
| SCHEMBL17432154 | 0.84 | DHODH (0.39) | DHODHLMNASMN1; SMN2PTGS2S1PR1 | |
| SCHEMBL20393848 | 0.83 | MEN1 (0.39) | LMNASMN1; SMN2PTGS2HPGDRORC | |
| SCHEMBL20393843 | 0.83 | PTGS2 (0.46) | PTGS2ATM | |
| SCHEMBL20393874 | 0.83 | LMNA (0.35) | LMNAHTTSMN1; SMN2S1PR1ACSS2 | |
| SCHEMBL20393710 | 0.83 | PTGS2 (0.42) | PTGS2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11083199-B2 | Heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-10 | — | — | US | disclosed |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018130443-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11083199-B2 | Heterocycle derivatives as pesticides | DDT, CBR3, CBR1 | NLRP3 1411/4885PTGER4 4361/4885DHODH 517/4885 |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CBR1 | NLRP3 1411/4885PTGER4 4361/4885DHODH 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.