Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393715 | 0.91 | RORC (0.36) | RORCPTGS2PTGS1CA12CA1 | |
| SCHEMBL20393710 | 0.91 | PTGS2 (0.42) | RORCPTGS2PTGS1CA12CA1 | |
| SCHEMBL21715802 | 0.89 | RORC (0.34) | RORCKCNH2S1PR1 | |
| SCHEMBL20393714 | 0.88 | PTGS2 (0.38) | RORCPTGS2PTGS1CA12CA1 | |
| SCHEMBL20393709 | 0.84 | RORC (0.33) | RORCKCNH2S1PR1 | |
| SCHEMBL20393844 | 0.82 | NPC1 (0.36) | PTGS2PTGS1CA12CA9KCNH2 | |
| SCHEMBL21715819 | 0.82 | CA1 (0.39) | RORCPTGS2PTGS1CA12CA1 | |
| SCHEMBL20386960 | 0.81 | CNR2 (0.33) | RORCS1PR1 | |
| SCHEMBL20393708 | 0.81 | PTGS2 (0.40) | PTGS2PTGS1CA12CA1CA2 | |
| SCHEMBL17422648 | 0.81 | PTGS2 (0.38) | RORCPTGS2PTGS1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130443-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | WO | disclosed |