Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20393710 | 0.89 | PTGS2 (0.42) | PTGS2CA12CA9KCNH2PTGS1 | |
| SCHEMBL20379045 | 0.86 | NPC1 (0.38) | NPC1RAB9APTGS2CA12CA9 | |
| SCHEMBL30194787 | 0.86 | NPC1 (0.38) | NPC1RAB9APTGS2CA12CA9 | |
| SCHEMBL20393716 | 0.86 | NPC1 (0.52) | NPC1RAB9APTGS2CA12CA9 | |
| SCHEMBL19366908 | 0.85 | KCNH2 (0.36) | PTGS2KCNH2DDR1PTGS1CNR2 | |
| SCHEMBL20393627 | 0.85 | NPC1 (0.35) | NPC1RAB9APTGS2CA12CA9 | |
| SCHEMBL20393624 | 0.83 | KCNH2 (0.31) | NPC1RAB9AKCNH2CNR2S1PR1 | |
| SCHEMBL21715798 | 0.83 | LMNA (0.37) | NPC1RAB9APTGS2KCNH2CNR2 | |
| SCHEMBL20393714 | 0.83 | PTGS2 (0.38) | PTGS2CA12CA9KCNH2PTGS1 | |
| SCHEMBL20393874 | 0.83 | LMNA (0.35) | NPC1RAB9ACA12CA9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11083199-B2 | Heterocycle derivatives as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2021-08-10 | — | — | US | disclosed |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018130443-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11083199-B2 | Heterocycle derivatives as pesticides | DDT, CBR3, CBR1 | NPC1 3182/4885RAB9A 892/4885PTGS2 3487/4885 |
| US-20200045976-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CBR1 | NPC1 3182/4885RAB9A 892/4885PTGS2 3487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.