SCHEMBL2039732

SCHEMBL2039732

O=C(O)c1cc(CCl)nn1-c1ncccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 1/20 0.38
SLC16A1 P53985 1/20 0.38
MALT1 Q9UDY8 2/20 0.37
MARS1 P56192 1/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GRN P28799 1/20 0.35
SORT1 Q99523 1/20 0.35
HIF1A Q16665 1/20 0.35
TRPA1 O75762 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MYC P01106 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31060003 1.00 SLC16A3 (0.38) SLC16A3SLC16A1MALT1MARS1LMNA
SCHEMBL423980 0.91 SLC16A3 (0.39) SLC16A3SLC16A1MALT1MARS1LMNA
Hydrochloric Acid SCHEMBL420241 0.90 SLC16A3 (0.38) SLC16A3SLC16A1MALT1MARS1LMNA
SCHEMBL16014771 0.88 SLC16A3 (0.38) SLC16A3SLC16A1MALT1MARS1LMNA
SCHEMBL30233893 0.88 SLC16A3 (0.40) SLC16A3SLC16A1MALT1MARS1GRN
SCHEMBL13084792 0.88 SLC16A3 (0.40) SLC16A3SLC16A1MALT1MARS1GRN
Hydrochloric Acid SCHEMBL957157 0.88 SLC16A3 (0.38) SLC16A3SLC16A1MALT1MARS1LMNA
Hydrochloric Acid SCHEMBL959170 0.87 SLC16A3 (0.36) SLC16A3SLC16A1MALT1KMT2A
SCHEMBL27749011 0.86 SLC16A3 (0.36) SLC16A3SLC16A1MALT1MARS1LMNA
SCHEMBL25008232 0.85 SLC16A3 (0.36) SLC16A3SLC16A1MALT1MARS1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor SYNGENTA CROP PROTECTION AG (CH) 2024-09-19 US disclosed
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2024-08-01 US disclosed
EP-4387449-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-26 EP disclosed
EP-4380363-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR Syngenta Crop Protection AG (CH) 2024-06-12 EP disclosed
CN-118076228-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-05-24 CN disclosed
CN-117813006-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-04-02 CN disclosed
WO-2023021020-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-23 WO disclosed
WO-2023012081-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-09 WO disclosed
EP-2513082-A1 NOVEL DIOXOLANE AND DIOXANE DERIVATIVES, AND A METHOD FOR THE PRODUCTION THEREOF Bayer CropScience AG (DE) 2012-10-24 EP disclosed
WO-2011073100-A1 NOVEL DIOXOLANE AND DIOXANE DERIVATIVES, AND A METHOD FOR THE PRODUCTION THEREOF BAYER CROPSCIENCE AG (DE) 2011-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240308988-A1 Method For Controlling Diamide Resistant Pests and Compounds Therefor DDT, NOS1, SLC11A2 SLC16A3 1408/4885SLC16A1 550/4885MALT1 2427/4885
US-20240251795-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR DDT, NOS1, SLC11A2 SLC16A3 1653/4885SLC16A1 820/4885MALT1 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.