SCHEMBL25008232

SCHEMBL25008232

N#CCc1cc(C(=O)O)n(-c2ncccc2Cl)n1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 2/20 0.36
SLC16A1 P53985 2/20 0.36
CNR1 P21554 2/20 0.36
TRPA1 O75762 1/20 0.35
MAPK10 P53779 1/20 0.35
MALT1 Q9UDY8 1/20 0.34
PTGS2 P35354 1/20 0.34
MARS1 P56192 1/20 0.34
KCNH2 Q12809 2/20 0.33
GCK P35557 1/20 0.33
DPP4 P27487 1/20 0.33
MCTS1 Q9ULC4 1/20 0.33
GRN P28799 1/20 0.33
SORT1 Q99523 1/20 0.33
HIF1A Q16665 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30233884 1.00 SLC16A3 (0.36) SLC16A3SLC16A1CNR1TRPA1MAPK10
SCHEMBL25008230 0.88 CNR1 (0.34) SLC16A3SLC16A1CNR1TRPA1MAPK10
SCHEMBL423980 0.86 SLC16A3 (0.39) SLC16A3SLC16A1TRPA1MALT1MARS1
Hydrochloric Acid SCHEMBL420241 0.85 SLC16A3 (0.38) SLC16A3SLC16A1TRPA1MALT1MARS1
SCHEMBL2039732 0.85 SLC16A3 (0.38) SLC16A3SLC16A1TRPA1MALT1MARS1
SCHEMBL31060003 0.85 SLC16A3 (0.38) SLC16A3SLC16A1TRPA1MALT1MARS1
SCHEMBL25008224 0.85 ALDH1A1 (0.43) SMN1; SMN2
SCHEMBL30233893 0.84 SLC16A3 (0.40) SLC16A3SLC16A1MALT1MARS1GRN
SCHEMBL16014771 0.84 SLC16A3 (0.38) SLC16A3SLC16A1TRPA1MALT1MARS1
Hydrochloric Acid SCHEMBL957157 0.84 SLC16A3 (0.38) SLC16A3SLC16A1TRPA1MALT1MARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076228-A Methods for controlling diamide-resistant pests and compounds thereof 先正达农作物保护股份公司 2024-05-24 CN disclosed
WO-2023012081-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-02-09 WO disclosed