Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.39 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL420241 | 0.99 | SLC16A3 (0.38) | SLC16A3SLC16A1MARS1MALT1LMNA | |
| Hydrochloric Acid SCHEMBL957157 | 0.97 | SLC16A3 (0.38) | SLC16A3SLC16A1MARS1MALT1LMNA | |
| SCHEMBL2039732 | 0.91 | SLC16A3 (0.38) | SLC16A3SLC16A1MARS1MALT1LMNA | |
| SCHEMBL13349718 | 0.91 | SLC16A3 (0.36) | SLC16A3SLC16A1MARS1MALT1TRPA1 | |
| SCHEMBL31060003 | 0.91 | SLC16A3 (0.38) | SLC16A3SLC16A1MARS1MALT1LMNA | |
| SCHEMBL13084792 | 0.90 | SLC16A3 (0.40) | SLC16A3SLC16A1MARS1MALT1GRN | |
| SCHEMBL11928300 | 0.90 | SLC16A3 (0.38) | SLC16A3SLC16A1MARS1MALT1TRPA1 | |
| SCHEMBL16014771 | 0.90 | SLC16A3 (0.38) | SLC16A3SLC16A1MARS1MALT1LMNA | |
| SCHEMBL30233893 | 0.90 | SLC16A3 (0.40) | SLC16A3SLC16A1MARS1MALT1GRN | |
| SCHEMBL27749011 | 0.87 | SLC16A3 (0.36) | SLC16A3SLC16A1MARS1MALT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340526-B2 | Process for preparing pyridyl-substituted pyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-17 | — | — | US | disclosed |
| US-20150191447-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-07-09 | — | — | US | disclosed |
| EP-2379526-B1 | Tetrazol-substituted anthranilic acid amides as pesticides | BAYER IP GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| US-8987460-B2 | Process for preparing pyridyl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2015-03-24 | — | — | US | disclosed |
| EP-2484676-B1 | Tetrazol-substituted anthranilic acid amides as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-01-21 | — | — | EP | disclosed |
| EP-2414345-B1 | Method for manufacturing Pyridyl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2014-09-17 | — | — | EP | disclosed |
| EP-2456747-B1 | Method for preparing alkoxyenones and enaminoketones | BAYER CROPSCIENCE AG (DE) | 2014-06-25 | — | — | EP | disclosed |
| EP-2456760-B1 | Method for manufacturing aryl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-8586753-B2 | Process for the preparation of 1-alkyl and 1-aryl-5-pyrazolecarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-19 | — | — | US | disclosed |
| US-8586753-B2 | Process for the preparation of 1-alkyl and 1-aryl-5-pyrazolecarboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20110152532-A1 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110152532-A1 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| US-20110087029-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-04-14 | — | — | US | disclosed |
| US-20110028729-A1 | Process for preparing aryl-substituted pyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-02-03 | — | — | US | disclosed |
| US-20110021782-A1 | Novel alkoxy enones and enamino ketones and a process for preparation thereof | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | US | disclosed |
| WO-2011009552-A1 | NOVEL ALKOXYENONES AND ENAMINOKETONES AND A METHOD FOR THE PRODUCTION THEREOF | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011009551-A1 | PROCESS FOR PRODUCING ARYL-SUBSTITUTED PYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-01-27 | — | — | WO | disclosed |
| EP-2243777-A1 | Method for manufacturing Pyridyl-substituted pyrazoles | Bayer CropScience AG (DE) | 2010-10-27 | — | — | EP | disclosed |
| WO-2010112178-A1 | METHOD FOR PRODUCING PYRIDYL-SUBSTITUTED PYRAZOLES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010069502-A2 | TETRAZOLE SUBSTITUTED ANTHRANILIC ACID AMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152532-A1 | Process For The Preparation Of 1-Alkyl And 1-Aryl-5-pyrazolecarboxylic Acid Derivatives | AADAC, CYP4X1, CYP4Z1 | SLC16A3 4612/4885SLC16A1 4345/4885MARS1 2311/4885 |
| US-20110028729-A1 | Process for preparing aryl-substituted pyrazoles | WNK3, WNK2, TYR | SLC16A3 3138/4885SLC16A1 4128/4885MARS1 3894/4885 |
| US-20150191447-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | PDXK, PLK2, WNK3 | SLC16A3 1755/4885SLC16A1 2255/4885MARS1 3056/4885 |
| US-20110087029-A1 | Process for Preparing Pyridyl-Substituted Pyrazoles | PDXK, PLK2, WNK3 | SLC16A3 1755/4885SLC16A1 2255/4885MARS1 3056/4885 |
| US-20110021782-A1 | Novel alkoxy enones and enamino ketones and a process for preparation thereof | AKR7A2, CYP51A1, PDK3 | SLC16A3 4068/4885SLC16A1 4722/4885MARS1 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.