Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18446121 | 0.95 | MGLL (0.46) | MGLL | |
| SCHEMBL22394230 | 0.80 | MGLL (0.72) | MGLL | |
| SCHEMBL20399930 | 0.79 | MGLL (0.51) | MGLL | |
| SCHEMBL20399228 | 0.74 | MGLL (0.48) | MGLL | |
| SCHEMBL18422184 | 0.74 | MGLL (0.71) | MGLL | |
| SCHEMBL20399534 | 0.72 | MGLL (0.41) | MGLLOPRM1OPRL1 | |
| SCHEMBL23566790 | 0.71 | MGLL (0.52) | MGLL | |
| SCHEMBL18446122 | 0.70 | MGLL (0.41) | MGLL | |
| SCHEMBL21625007 | 0.68 | MGLL (0.32) | MGLL | |
| SCHEMBL20399266 | 0.68 | MGLL (0.51) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134698-A1 | HETEROCYCLIC SPIRO COMPOUNDS AS MAGL INHIBITORS | PFIZER INC. (US) | 2018-07-26 | — | — | WO | disclosed |