Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21625015 | 0.93 | MGLL (0.31) | MGLL | |
| SCHEMBL21625009 | 0.80 | MGLL (0.37) | MGLL | |
| SCHEMBL21625014 | 0.78 | MGLL (0.44) | MGLL | |
| SCHEMBL20399926 | 0.75 | MGLL (0.46) | MGLL | |
| SCHEMBL18446121 | 0.72 | MGLL (0.46) | MGLL | |
| SCHEMBL20399264 | 0.68 | MGLL (0.48) | MGLL | |
| SCHEMBL360600 | 0.68 | — | — | |
| SCHEMBL21636210 | 0.65 | MGLL (0.43) | MGLL | |
| SCHEMBL360415 | 0.65 | PRKCA (0.41) | — | |
| SCHEMBL21625008 | 0.64 | MGLL (0.39) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3823723-A1 | HETEROCYCLIC SPIRO COMPOUNDS AS MAGL INHIBITORS | Pfizer Inc. (US) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020016710-A1 | HETEROCYCLIC SPIRO COMPOUNDS AS MAGL INHIBITORS | PFIZER INC. (US) | 2020-01-23 | — | — | WO | disclosed |