Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20412560 | 0.82 | P2RX7 (0.37) | P2RX7MAPK1 | |
| SCHEMBL31387272 | 0.79 | P2RX7 (0.44) | P2RX7MAPK1 | |
| SCHEMBL3710492 | 0.70 | OPRD1 (0.42) | — | |
| SCHEMBL3710496 | 0.70 | OPRD1 (0.42) | — | |
| SCHEMBL378063 | 0.70 | P2RX7 (0.46) | P2RX7MAPK1 | |
| SCHEMBL20606348 | 0.70 | P2RX7 (0.54) | P2RX7MAPK1 | |
| SCHEMBL1441509 | 0.70 | P2RX7 (0.46) | P2RX7MAPK1 | |
| SCHEMBL370271 | 0.69 | P2RX7 (0.41) | P2RX7MAPK1 | |
| SCHEMBL986716 | 0.68 | P2RX7 (0.51) | P2RX7MAPK1 | |
| SCHEMBL23243025 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134695-A1 | 1,1,1-TRIFLUORO-3-HYDROXYPROPAN-2-YL CARBAMATE DERIVATIVES AS MAGL INHIBITORS | PFIZER INC. (US) | 2018-07-26 | — | — | WO | disclosed |