SCHEMBL20400588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30400781	1.00	UCHL5 (0.55)	UCHL5UCHL1UCHL3ADORA2ACDC7
	SCHEMBL20436605	0.90	ADORA2A (0.48)	UCHL5UCHL1UCHL3ADORA2ACDC7
	SCHEMBL20400757	0.89	ADORA2A (0.52)	UCHL5UCHL1UCHL3ADORA2ACDC7
	SCHEMBL20436595	0.89	ADORA2A (0.62)	ADORA2ACDC7DAPK3ROCK2PAK4
	SCHEMBL20436604	0.87	ADORA2A (0.51)	ADORA2AADORA2BCYP19A1KLKB1ADORA1
	SCHEMBL20401627	0.87	ADORA2A (0.47)	UCHL5UCHL1UCHL3ADORA2ACDC7
	SCHEMBL20442118	0.87	ADORA2A (0.48)	ADORA2ACDC7DAPK3ROCK2PAK4
	SCHEMBL20400564	0.86	ADORA2A (0.49)	UCHL5UCHL1UCHL3ADORA2ACDC7
	SCHEMBL20416965	0.85	ADORA2A (0.50)	UCHL5ADORA2AADORA2BCYP19A1ADORA1
	SCHEMBL30401332	0.85	ADORA2A (0.50)	UCHL5ADORA2AADORA2BCYP19A1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.