SCHEMBL20400757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20400588	0.89	UCHL5 (0.55)	ADORA2AADORA2BCYP19A1KLKB1CDC7
	SCHEMBL30400781	0.89	UCHL5 (0.55)	ADORA2AADORA2BCYP19A1KLKB1CDC7
	SCHEMBL20436604	0.89	ADORA2A (0.51)	ADORA2AADORA2BCYP19A1KLKB1ADORA1
	SCHEMBL20436595	0.89	ADORA2A (0.62)	ADORA2AADORA2BCYP19A1CDC7DAPK3
	SCHEMBL20400924	0.87	ADORA2A (0.50)	ADORA2AADORA2BCYP19A1ADORA1
	SCHEMBL20400183	0.87	ADORA2A (0.52)	ADORA2AADORA2BCYP19A1KLKB1CDC7
	SCHEMBL20436589	0.87	ADORA2A (0.51)	ADORA2AADORA2BCYP19A1KLKB1ADORA1
	SCHEMBL20400564	0.86	ADORA2A (0.49)	ADORA2AADORA2BCYP19A1KLKB1CDC7
	SCHEMBL20400624	0.85	ADORA2A (0.49)	ADORA2AADORA2BCYP19A1KLKB1CDC7
	SCHEMBL30402140	0.85	ADORA2A (0.49)	ADORA2AADORA2BCYP19A1KLKB1CDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.